American Airlines has announced the safety-related cancellation of about 600 flights scheduled for Friday. More than 3,o00 American Airlines flights have been cancelled since the airline -- the world's largest air carrier -- started grounding and inspecting its MD-80 aircraft on Tuesday. An American Airlines announcement states that "additional inspections of our MD-80 fleet are being conducted to ensure precise and complete compliance with the FAA's directive related to wiring in the aircraft's wheel wells." The airline hopes to end the flight cancellations by the end-of-day Saturday. The American Airlines website is providing information about ticket refunds and compensation for customers who have been forced to make overnight stays due to the flight cancellations.